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Perricone MD Acne Relief Maximum Strength Spot Gel's invisible gel works overtime to help reduce blemishes and help prevent future breakouts by unclogging pores and absorbing excess oil without over-drying. It addresses blemishes, whiteheads, and blackheads. How do I use it: Clean the skin thoroughly before applying this product. Cover the entire affected area with a thin layer one to three times daily. From Perricone MD. Includes: